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doi: 10.1016/j.pmedr.2018.02.007 77
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No adverse effects were reported, but rigorous, large-scale trials are lacking, according to NIH
Before human translation, essential parameters to define: optimal dosing, infusion/administration route, frequency, biomarkers to monitor (senescent cell burden, inflammatory cytokines, organ function), long-term follow-up for adverse outcomes (especially tumour risk)
Here is where the conversation gets critical, and where many people unknowingly put themselves at risk
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