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Among them, GLP-1 and GIP (gastric inhibitory polypeptide) are known as incretins, gut-derived hormones that enhance glucose-dependent insulin secretion, playing a pivotal role in maintaining glucose homeostasis and serve as important therapeutic targets for type 2 diabetes and obesity
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Glucagon-Like peptide 1/glucagon receptor dual agonism reverses obesity in mice
L-CARNITINE may help delay muscle fatigue and improve endurance
The refined TED outcome, which focuses on pathognomonic manifestations, followed the same trend, showing a protective effect at all time points, including a one-year risk of 0.42% in the GLP-1 group compared to 0.53% in the control group (HR 0.79)
Given its biological effects, activation of GLP-1R has been explored as a latent treatment for metabolic disorders like type 2 diabetes mellitus (T2DM) and obesity
