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Theoretical concerns with chronic high-dose use include organ enlargement and exacerbation of active malignancy via IGF-1 axis growth signaling
[Anticancer drugs targeting glutathione S-transferase ] [PMID: 29856577] Laboratory literature summary: [Anticancer drugs targeting glutathione S-transferase ]
Scoring system assessing mucosal visibility of upper gastrointestinal tract: the POLPREP scale
Patients may experience a temporary increase in gastrointestinal symptoms with each dose increase, though these usually resolve within one to two weeks
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