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The quite unexpected positive cardiorenal outcomes that have emerged from the cardiovascular outcomes trials (CVOTs) with both glucagon like peptide-1 receptors agonists (GLP-1RA) and sodium-glucose co-transporter 2 (SGLT-2) inhibitors have produced a shift of diabetes management from the meticulous glycemic control alone to the simultaneous improvement of CV outcomes
For reference, this is equal to around 7.5% of Lillys total revenues in fiscal 2024
Testa G, Mora-Maltas B, Camacho-Barcia L, Granero R, Lucas I, Agera Z, et al
Providers typically begin with lower doses to help reduce gastrointestinal side effects and improve overall tolerability
Look for D3 in softgel form (oil-based) rather than tablets for better bioavailability, and always take it with food containing fat
They are typically utilized when an FDA-approved drug is unavailable or when the approved version is unsuitable due to specific medical requirements, such as an allergy or the necessity of a different dosage form or formulation.
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