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Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, et al

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Children or their care givers were asked to rate the intensity of each individual symptom on a validated 5-point Likert scale (0 indicates no problem, 1 indicates mild problem, 2 indicates moderate problem, 3 indicates severe problem and 4 indicates very severe problem)

Proposed neuroprotective mechanisms included attenuation of oxidative stress, mitigation of hypoxia triggered cell death, and dampening of the inflammatory response after acute ischemic injury