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Ipamorelin's human data is limited to two published pharmacokinetic/pharmacodynamic studies: a 1999 PK/PD study (PMID: 10496658) that documented dose-response relationships and peak GH at 30-40 minutes post-injection in human volunteers, and a completed Phase II clinical trial for postoperative ileus (NCT00672074), after which ipamorelin's development for this indication was discontinued without approval

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Analytical Method Solutions: Purity Assessment: High-performance liquid chromatography (HPLC) coupled with ultraviolet (UV) detection, and mass spectrometry (MS) is essential for assessing therapeutic peptide purity