Because they are not real GLP-1 drugs
Today, medical guidelines remain cautious, but they now recognize that GLP-1s might help some people with type 1 diabetes, especially those with insulin resistance or excess weight
In contrast, excessive or sustained activation of TLRs can promote chronic inflammation and has been implicated in the pathogenesis of numerous immune-mediated disorders (262)
HELPING MILLIONS OF PEOPLE ACHIEVE THEIR HEALTH & FITNESS GOALS
The study also shows that ISR and OSR, acting independently of CoA depletion, also increase the production of the stress hormone GDF15, which contributes to food aversion and degradation of acetyl-CoA-carboxylase, a key enzyme in lipid biosynthesis
The FDA-reported adverse event databases do not list alopecia as a primary side effect of these medications