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What This Means for Tirzepatide Response Tirzepatide's GIP receptor agonism directly improves beta-cell function and insulin sensitivity, making it particularly well-suited for patients with high baseline insulin resistance

[31] [32] Patients with type 2 diabetes taking tirzepatide often have multiple overlapping risk factors, including advanced age, metformin use, and potential dietary restrictions, making them a particularly vulnerable population requiring vigilant monitoring

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The makers recommend that you don't take it two months before you plan to get pregnant