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Avoid anything coarser than 29G for routine GLP-1 injections
Wharton S, Batterham RL, Bhatta M, et al
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That gap in supply has given a boost to compounding pharmacies (who are allowed to produce customized versions of drugs, OR identical versions of drugs that are in short supply i) and online prescribing platforms
The action on kidneys appears to be directly through the effects also on renin-secreting cells of the juxta-glomerular apparatus, whose stimulation may lead to increased natriuresis and reduce hyperfiltration, and indirectly by the reduction of angiotensin II levels, the increase in nitric oxide with consequently endothelial vasodilation and the improvement of risk factors of kidney disease (hyperglycemia, hypertension, obesity) (20)
Phentermine can also cause gastrointestinal disturbances, including dry mouth, constipation, and rarely, diarrhea
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