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doi: 10.1038/leu.2009.149 115 WalkerBABoyleEMWardellCPMurisonABegumDBDahirNMet al

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Participants in trials have experienced an average weight loss of up to 24% of their body weight over the course of the study

Instead, alkyl halides are converted to thiols via an S -alkylation of thiourea

"Based on currently available information (primarily from clinical trials), the types of side effects associated with ecnoglutide are expected to be similar to those of existing GLP-1 receptor agonists (such as semaglutide or dulaglutide), primarily including gastrointestinal disorders (diarrhea, nausea, vomiting) and decreased appetite