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Certain MNPs can cross the bloodbrain barrier and accumulate in the mouse brain, potentially leading to neurotoxicity and cognitive dysfunction ( 2.4.9 Association between microplastics and stroke Current evidence indicates that microplastics may increase the risk of stroke occurrence by inducing inflammatory responses and oxidative stress ( Recent clinical studies have demonstrated the presence of micro- and nanoplastics (MNPs) within carotid artery plaques, with these patients exhibiting a higher propensity for vascular events, one study ( 3 How to mitigate the impact of microplastics on the CNS The study ( Danio rerio )