Bacterial contamination poses acute health risks
BlakeDDWeathersFWNagyLMKaloupekDGGusmanFDCharneyDSet al
The review confirmed that NNMT-mediated NAD+ depletion impairs mitochondrial function, SIRT activity (particularly SIRT1 and SIRT3), redox balance, and energy metabolism, creating conditions relevant to cardiovascular disease research models
In the United States, alone, deaths due to heart and vascular disease unnecessarily kill almost 1 million people every year
The primary role of GSTs is to detoxify xenobiotics by catalyzing the nucleophilic attack by GSH on electrophilic carbon, sulfur, or nitrogen atoms of said nonpolar xenobiotic substrates, thereby preventing their interaction with crucial cellular proteins and nucleic acids
Nat Rev Cancer 7:778790