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Frequent bouts of vomiting can cause severe dehydration, malnutrition, irritation, and injuries to the esophagus, acidic erosion of the tooth enamel, root canal infection, and tooth loss

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Berberine should also be used cautiously by anyone on blood sugar lowering medications because the combined effect could cause hypoglycemia

In the SURPASS program, gastrointestinal side effects associated with the use of tirzepatide were similar to those observed with semaglutide and GLP1-RA drugs in general, both in terms of frequency and duration [3]

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