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The small molecule drug CA-074-methyl ester reduces lipid peroxidation and mitochondrial dysfunction in macrophages by inhibiting cathepsin B, thereby alleviating ferroptosis and inducing polarization of M2 macrophages, promoting the recovery of nerve function in mice after SCI
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Sugimoto Y, Tsukahara S, Sato S, Suzuki M, Nunoi H, Malech HL et al
Ease of Use : Self-administered at home with no need for mixing or priming
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