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A single molecule activates GIP, GLP-1, and glucagon receptors
The peptide also enhances the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), critical molecules for neuronal survival and plasticity
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Safety First: What Researchers Need To Know Because the number of clinical trials is still small, safety is a top concern in research labs
In addition, since some studies have also recorded failure in antioxidant supplementation efficacy, optimal design of clinical trials in terms of targeted delivery of antioxidants, clinical pathology and concentration dependent dosage schedule is needed to go ahead in the knowledge and future application of this kind of treatment in CIPN (Kamat et al., Future consideration Taking in account the scientific evidence summarized in this review, NP is a complex network of several molecular processes, including nitro-oxidative stress, immune response, and TRP channels activation, among others
2020 Oct-Dec;10(4):155-162
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