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The review findings for how GLP-1s affect substance abuse disorders were largely promising, but the authors note that human studies are mostly in the early stages

Sadeghipour P, Talasaz A, Rashedi S, Jamalkhani S, Ghoshouni H, Babaei M, Kohansal E, Mohebbi B, Elahifar A, Omidvar R, Hadavand N, Hassanvand M, Poopak A, Bakhshandeh H, Mazloomzadeh S, Kakavand H, Aghakouchakzadeh M, Piazza G, Krumholz H , Bikdeli B

Underutilization of AUD medications is attributed to multiple factors, including few Food and Drug Administration (FDA)approved therapies, limited awareness of these medications, and barriers related to stigma, wrote a team of investigators led by Christian Hendershot, Ph.D., director of clinical research at University of Southern Californias Institute for Addiction Science and associate professor at Bowles Center for Alcohol Studies

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The human samples were collected by Red Cross blood donor service and Aurea biobank according to ethical permits of the biobanks and shared based on research collaboration to this study