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Gong et al., 2025, DOI)
MOTS-c MOTS-c is a mitochondrial-derived peptide
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8 Just like GLP-1, the GIP (glucose-dependent insulinotropic polypeptide) pathway is activated primarily after meals, but performs different functions
TIRZEPATIDE: EFFICACY IN PHASE III CLINICAL TRIALS After the promising results in Phase I and Phase II trials, the SURPASS clinical trial programs were designed to assess the efficacy and safety of Tirzepatide as a treatment to improve glycaemic control in patients with T2D
Our findings pave the way for further evaluation of the performance of NAM toolboxes for a wider substance dataset with varied mechanisms of action, uses, and balanced low and high-risk benchmarks to build confidence in the protectiveness of the approach
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