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Presented for research literature review only Watanabe T et al

Inject while the area is still numb

The lower expression of epithelial adhesion molecules, such as DDR1 and E-cadherin, facilitates damage to melanocytes and exposure of antigens that favor autoimmunity

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One patch worn At least 8 hours every day for 90 days is recommended for significant anti-aging and whitening benefits, but some results may be experienced in as fast as few weeks

This is a central mechanism distinct from peripheral vasodilators