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Carrying extra weight means these areas must manage more stress throughout the day, which can contribute to stiffness, soreness, or reduced ease of movement

This typically occurs during the first few weeks of treatment or following dose increases and often improves with time as the body adjusts

In one randomized controlled trial, people with moderate-to-high daily stress engaged in mindfulness-based stress reduction (MBSR) and cognitive behavioral therapy (CBT)

The danger is too great.

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The broad search algorithm combined index terms and free-text words for all GLP-1-RAs, with no restriction to study language, design (including both individual studies and their meta-analyses), setting, comparator and outcome of interest to maximize the comprehensiveness of the evidence synthesis