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According to the MHRA/EMC SmPC, these include: Vomiting reported in approximately 8% of patients Abdominal pain and discomfort cramping or bloating may make it difficult to find a comfortable sleeping position Acid reflux or heartburn which can worsen when lying down Hypoglycaemia (low blood glucose) may occur, particularly when Ozempic is used in combination with sulphonylureas or insulin

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Many charts do not explain screening criteria, adverse-event rules, missed-dose handling, or why investigators chose a particular pattern

Even with reduced hunger, calorie intake may creep upward through larger portion sizes, snacking patterns, or reduced physical activity

Yes, gradually over several weeks to months, maintaining results requires ongoing use or periodic cycles

Some clinicians recommend reducing to the lowest effective dose for several weeks while intensifying behavioral interventions, though this approach lacks formal validation