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The GLP-1R interacts with structurally related peptide hormone ligands, such as glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), parathyroid hormone, etc

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Finally, delineating tissue-preferential effects is essential to determine whether improvements in IR arise primarily from reduced hepatic lipid content or also involve amelioration of pancreatic steatosis and skeletal muscle lipid metabolism

The pellets after solubilization and supernatants for each treatment were electrophoresed on a denaturing gel (Fig

Bonhof GJ, et al