Understanding GLP-1 Agonists and Their Side Effects GLP-1 agonists, such as exenatide (Byetta), liraglutide (Victoza), and dulaglutide (Trulicity), work by stimulating insulin secretion, suppressing glucagon release, and slowing gastric emptying, leading to improved blood sugar control and reduced appetite
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Pathophysiology of irritable bowel syndrome
Cultures were pulse-labeled with 10 M BrdU (a nucleoside analog that competes with thymidine for incorporation into DNA) in DMEM-10% HS for the final 2-h period of 48-h in culture, followed by immunocytochemistry for detection of BrdU using G3G4 anti-BrdU mAb (1:100 dilution) and HRP-conjugated anti-mouse IgG Ab (1:500 dilution)
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Once the free radicals cross the barrier, they target the brain cells