Its primary mechanism of action is the sequestration of G-actin , which mobilizes the actin cytoskeleton for cell migration, wound closure, and tissue regeneration
If patients do not tolerate the maintenance dosage of 2.4 mg once weekly, the dosage can be decreased to 1.7 mg once weekly
Phase 1b: 20 obese patients with NAFLD (non-alcoholic fatty liver disease) received 25 mg per day subcutaneously for 4 weeks
GLP-1 receptor agonists are administered subcutaneously into the abdomen, thigh, or upper arm with no clinically relevant absorption differences between sites
This protocol allows patients to focus on optimizing their nutrition, particularly protein intake, which is essential for proper wound healing and recovery
Wait at least 2-3 hours after eating before injecting, and avoid food for 30-60 minutes afterward