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Importantly, TEG cannot be regarded as an experimental or interventional model
Research from clinical trials indicates that most patients regain weight after stopping semaglutide
"Triplehormone-receptor agonist retatrutide for obesitya phase 2 trial." New England Journal of Medicine 389.6 (2023): 514-526
As research progresses, these molecules could lead to groundbreaking therapies, providing new hope for patients and healthcare providers alike
Experimental studies have demonstrated that chronic hyperglycemia may reduce -cell expression of GLP-1 receptors, leading to diminished responsiveness to endogenous GLP-1 [7, 10]
The mechanism involves sympathetic nervous system activation and direct stimulation of gut hormone release
