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Mitochondrial Ca 2+ overload also triggers apoptotic cell death by increasing ROS production and opening the mPTP [96]

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doi: 10.1186/s13643-019-1202-6 25 PetersonSMcAninchEBiancoA

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Glutathione protects astrocytes from peroxynitrite-mediated mitochondrial damage: implications for neuronal/astrocytic trafficking and neurodegeneration

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