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Acknowledgments We are grateful to Dr

Remember also that cells expressing both receptors display IR/IGF-1R hybrids whose proportion tracks relative expression, so even a clean IGF-1R-dependent result may be partly hybrid-mediated

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In particular, N-oleoyl serinol (N-OS) is described as a potent GPR119 agonist, acting in the lower micromolar range with twice the efficacy of the endogenous ligand OEA (394)