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Prior authorization for Wegovy (semaglutide for weight loss) typically requires: Being obese, meaning a body mass index (BMI) of 30 or higher, or Being overweight (having a BMI of 27 or higher) with one or more weight-related health conditions such as diabetes, high blood pressure, or high cholesterol

Its degraded by proteolytic enzymes, not by cytochrome P450 liver enzymes

Understanding the difference between research and pharmaceutical peptides provides essential context for this decision