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86.4% achieved 5% or more weight loss

Why muscle preservation matters beyond appearance A 22-RCT network meta-analysis of 2,258 participants found lean mass accounts for roughly 25% of total weight lost on GLP-1 drugs, with DXA substudies reporting 2640%

Zhao H, Liu Y, Liu M, et al

However, animal studies have shown that taking semaglutide during pregnancy may increase the risk of birth defects, miscarriage, and delivering babies that are small for their gestational age

4) They are anti-inflammatory

Glucagon receptor activation has been associated with modest increases in calcium absorption and bone formation markers in preliminary studies, though this data is not yet definitive enough to call it a proven benefit