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Hence, we hypothesised that GLP-1 signalling in the OB could control the neural circuitry that regulates energy homeostasis in the context of metabolic disorders

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Lancet Diabetes Endocrinol (2021) 9:48490

95% CI 0.87, 0.95) was significantly lower in the GLP-1RAs group

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Examination of circulating inflammatory markers showed that RETA moderately increased IL-6 concentrations, whereas withdrawal significantly elevated plasma IL-6 concentrations compared to Veh