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For GI-local effects, oral administration makes mechanistic sense
Which in turn leads to weight loss
It doesnt fully metabolize in the body, meaning roughly 90% exits through urine, delivering sweetness without calories.
Studies have reported significant tirzepatide weight loss results, with some participants losing more than 20% of their body weight when combined with lifestyle modifications
ASH25-0015422-02A2)
A: Yes, gradually
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