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Together, these pathways create a primed-and-fire mechanism that exceeds the output of either pathway alone
These mechanisms manifest as several distinct but interconnected pathophysiological features that contribute to the clinical presentations of the disease
In parallel, we observed upregulation of canonical NRF2 target genes such as Gclc and Gclm , supporting the conclusion that melatonin augments NRF2 transcriptional activity in ILC2s
doi: 10.1038/s41467-023-44304-w 132 TetlowLCWoolleyDE
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The levels of GHK-Cu in the body decrease as we age
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