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PMCID: PMC10855385
The pathway operates through both canonical (RBP-J/CBF-1dependent) and noncanonical mechanisms
According to the working model, these cysteine residues may undergo chemical modification/remodeling including trisulfide bond formation and/or related reactions, resulting in a regional (minor, but effective) structural alteration that enhances c-met binding and the nitration resistance of Y198-HGF
The highest amounts of glutathione are found in the liver and kidneys, which are responsible for the removal of toxic components
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Lastly, while no significant difference was observed in the overall symptom score between groups, specific hyperthyroid symptoms were significantly lower in the intervention group, including irritability, tremor, mood lability, heat intolerance, and exertional dyspnea
