that video is linked here below
The rate shows a clear dose-response pattern: in the SURMOUNT-1 trial published in the New England Journal of Medicine (N=2,539 adults followed for 72 weeks), reported rates climbed from roughly 12% at the 2.5 mg starting dose to 23% at the 15 mg top dose, compared to about 8% on placebo
Fielding et al
Important Note Severe, persistent abdominal pain radiating to the back requires immediate medical evaluation as this may indicate pancreatitis, a rare but serious complication
While individual results vary, these timelines are common: 10 pounds: often within 610 weeks 20 pounds: often within 35 months People with higher starting weights may lose weight faster initially, while others lose more gradually
Both ISR and NTLP contribute to higher MACEs rates, emphasizing the need for effective therapeutic strategies to inhibit coronary lesion progression