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Retatrutide Phase 2 (Jastreboff et al., NEJM 2023) reported 24.2% weight loss at 48 weeks at 12 mg
Patients who choose surgery or GLP-1 RA medications to treat obesity should also commit to lifestyle modifications for the best chance of success
doi: 10.1016/j.bbrc.2022.01.106 201 MuriJ.KopfM
Physicians, and other relatively high earning individuals have availed themselves of these peptides to their benefit for some time, but significantly overweight Medicare patients who dont have a spare $300-$500 / month have not had access to this class of medications
The main risk is to believe that the effect depends on a specific drink or program and then to return to old habits even stronger: alternating restriction/compensation, which creates more instability than a stable routine
Dysregulation of iron metabolism-linked genes at myocardial tissue and cell levels in dilated cardiomyopathy
