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Researchers noted multiple study limitations, including use of records from health care organizations within the federated health research network TriNetX that may not be nationally representative, they wrote

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Clinical trials show that patients typically lose between 2 to 4 pounds during the first four weeks at this entry-level dose, though individual results vary based on metabolism, lifestyle, and genetic factors

Some scientific research has suggested that it may improve insulin sensitivity and support metabolic pathways, which may indirectly influence energy metabolism and weight management