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In obese patients, acipimox can inhibit adipose tissue lipolysis by activating protein upregulated in macrophage by INF- (PUMA-G) (also known as the hydroxycarboxylic acid receptor 2 [HCA2] and GPR109a) receptors

In ovariectomized mice (an animal model for menopause), estrogen replacement increased GLP-1 secretion from both intestinal L-cells and pancreatic alpha-cells

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STR upregulated more immunometabolic-relevant proteins post infusion (13 vs

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