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In preclinical studies, MOTS-c treatment in mice fed a high-fat diet prevented obesity and improved insulin sensitivity to a degree comparable to exercise PMID: 25565208
Shirley MA, Hu P, Baillie TA (1993) Stereochemical studies on the -oxidation of valproic acid in isolated rat hepatocytes
doi: 10.1104/pp.108.118919 76 DemidchikV
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So they are valuable in research on muscle growth, bone health and physical performance markers in controlled laboratory settings
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