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Data show that deficiency of claudin-5 and occludin in cortical brain regions associated with AD further drives a loss of adhesion between TJs (Yamazaki et al., 2019)
They are prescribed SSRIs, Benzodiazepines, and Antipsychotics
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Morgenroth reported nanogel-based carrier for the intracellular delivery of radiophamaceuticals to brain tumor cells by functionalization of ligands of diphtheria toxin receptor overexpressed in abnormal cerebral blood vessels
When results fall in this borderline range, a methylmalonic acid test is recommended to confirm whether a functional deficiency exists
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