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Subcutaneous injections deliver the drug directly into the bloodstream, ensuring immediate bioavailability, whereas transdermal patches continuously deliver the drug through the skin

2019;181:R21134

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Persistent hyperglycemia can mediate hypoxic or ischemic injury, as well as elicit cardiomyocyte contractile dysfunction and the NF-B signaling pathway activation, thus inducing ER stress [152]

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