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B12 is water soluble, which means B12 doesnt build up in your system once youre at the appropriate amount for your body you will just eliminate any extra, so theres very little risk of an overdose

As well, some people may have allergies or medical conditions that do not allow them to be a good candidate to receive vitamin B12 shots, such as kidney problems, low potassium levels, deficiencies in other vitamins such as iron or folic acid, or just an allergy or sensitivity to vitamin B12 itself

How to give Neurobion injection safely

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A pattern of 12 weeks on, 4-6 weeks break, repeated several times, produces sustainable results without the receptor desensitization that can occur with extremely long continuous use

Use an insulin syringe (29 to 31 gauge, 0.5 mL or 1 mL)