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From early fad diets, through to modern metabolic research, the episode explains why calorie restriction often backfiresand why fueling the body is key to long-term health

This flexibility is particularly valuable for GLP-1 medications, where dose titration schedules can benefit from fine-tuning that commercial products don't allow

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instead, decrements are observed

Some hallmarks include: To try to prevent facial changes associated with rapid weight loss, consider a more gradual approach instead