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Excessive long-term use of B6, particularly at doses above 200 milligrams daily sustained over months, can cause sensory neuropathy

Goldstein et al., 2005)

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(2021) 22:e13189

Research facilities using 5 Amino 1MQ capsules benefit from implementing quality control measures to ensure compound integrity during storage

Yes, rapid improvement in glycemic control with any diabetes medication can occasionally trigger treatment-induced neuropathy of diabetes, which presents as acute painful neuropathy and typically improves over time