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To date, we have identified 25 genetically encoded selenoproteins in human, including glutathione peroxidase (GPx), thioredoxin reductase (TXNRD), and iodothyronine deiodinases (DIOs), which have a wide range of functions, from anti-inflammatory and antioxidant activities to thyroid hormone metabolism

According to a preclinical study of APG-115 in AML patients, APG-115 strongly inhibits proliferation and promotes apoptosis through activation of the p53/p21 pathway in wild-type p53-expressing AML cells and in vivo

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We found that the amount of AngIV in mouse tissue increased after the administration of Dihexa compared to that in the WT group

Long chain acetylcarnitine esters transport fatty acyl moieties into the mitochondria (Figure 2)