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This targeted response reduces hypoglycemia risk dramatically compared with older diabetes drugs

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It also enables us to gather necessary real-world data to better understand how patients react to these medications, how they all interact, and who develops side effects

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As previously noted, even the lowest effective 4mg aw dose provided compelling health benefits It will be compelling to see how triple-agonist therapy is tolerated in the long term especially given that single and dual incretin-based therapies show substantial discontinuation rates in real-world settings, in some cohorts approaching 70%