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There is an opportunity over time to renegotiate contracts with the manufacturers to increase operating margins to more industry average levels, but that is a multi-year process

PMID 22622578

Besides the extended life span, the overexpression of histone proteins may also be associated with increased DNA expression and repair because irradiation-induced DNA damage was shown to downregulate histone gene transcription via the G1 checkpoint pathway 77

Provides a stable formulation for research protocols requiring precise compound combinations

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