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Eighth: failing to adjust budget models when litigation shifts an LOE date

DOI: 10.1016/S2213-8587(17)30018-0 2

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100% IM) IM bioavailability: ~100% Tmax: 12-24 hours (SC), 6-12 hours (IM) Half-life: 29-36 hours (allows for 2-3x/week dosing) Renal clearance: primary Detection: urine/serum up to 7-14 days post-administration Applications, Mechanisms, and Extended Research 1

DSIP or vehicle was administered intranasally at a dosage of 120 g/kg (n a volume of 100 L/kg