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Pancreas 45(10):13861393
Implications for age-related macular degeneration
73 Mitochondrial-derived peptides (MDPs) are encoded by short open reading frames within mtDNA, including humanin, small humanin-like peptides 1-6 (SHLP1-6), MOTS-c, and CYTB-187AA
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Therefore, aerobic exercise can modulate oxidative stress in brain tissue, inhibit lipid peroxidation and ferroptosis, and mitigate neurological deficits
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