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Data from the 2024 STEP-4 trial indicates that 80% of individuals who stop medication entirely regain significant weight within 52 weeks

[44] While initially thought to be solely a byproduct of rapid weight loss, the exact mechanism may involve reduced gallbladder motility and changes in bile acid composition

This has a profound effect on both blood sugar control and appetite regulation, which often results in weight loss

This includes bills, receipts, pay stubs, and any other evidence of economic impact

As patients experience significant physical improvements, their mental health often gets a much-needed boost

1 Similarly, the active ingredient tirzepatide is marketed by Eli Lilly as two separate drugs under the brand names Mounjaro (injection for diabetes, approved in 2022) and Zepbound (injection for weight loss, approved in 2023)