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The phosphorylated analogue P-DSIP has been reported to produce larger increases in slow-wave and paradoxical sleep than the parent peptide in unrestrained rats under continuous nocturnal infusion (Yehuda & Mostofsky, 1989)

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Mol Neurobiol 57:23142332

Proper PT-141 dosing protocols vary between delivery methods, with nasal formulations often requiring slightly higher doses to match injectable potency

That makes it a useful reference compound in this area of study

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