The DDC gene is located on chromosome 7p12.2p12.1 and is composed of 18 exons that generate seven alternatively spliced mRNAs that collectively encode six isoforms of the enzyme
Support collagen and elastin integrity
The median time to onset was 2.5 months (range 0 days3 years)
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Substrates were added in a stepwise fashion in the following order (final concentrations) 0.2 mM palmitoyl carnitine, 1 mM malate, 4 mM ADP, 0.4 mM octanoyl carnitine, 5 mM pyruvate, 10 mM glutamate, 10 mM succinate, 1 M CCCP, 2 M rotenone, and 5 M Antimycin A
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